Mycophenolate mofetil added to a regimen with cyclosporine A will lower CsA.

2003 OCT 9 - (NewsRx.com & NewsRx.net) -- Mycophenolate mofetil added to a regimen with cyclosporine A will lower it (CsA); higher doses may be needed.

"Unexpectedly lower CsA 2-h levels were found in patients who received additional immunosuppression by MMF in our center. The aim of this study is to prove whether there are differences in CsA metabolization when MMF is added to treatment. In 33 children who received an immunosuppression regime of prednisolone and CsA, as well as in 15 children who were treated with additional MMF, C2 and C0 were taken," scientists writing in the journal Pediatric Transplantation report.

"In 11 children, full AUC of CsA was …